Ok here are two "problems" i encountered.
First: Iris tends to loose its taget mode when you're clicking to fast. This is extremly nasty if you got a long way to .m tele
Dunno if this can be fixed.
Second: Because of the 3Ds you have to use rotate Cam alot. I (and i think most ppl) use the left Mouse button to "left click" and rotate the cam. The problem is: if you got a target cursor ready you wont be able to rotate the cam using that button. It would be nice if the target cursor behaves like in the original uo client: Don't execute the command if you are trying to drag-drop something or when you're rotating the cam. Dunno if this is possible